Collagen I formation

Most collagen forms in a similar manner, but the following process is typical for type I:

1. Inside the cell
   1. Two types of peptide chains are formed during translation on ribosomes along the rough endoplasmic reticulum (RER): alpha-1 and alpha-2 chains. These peptide chains (known as preprocollagen) have registration peptides on each end and a signal peptide.
   2. Polypeptide chains are released into the lumen of the RER.
   3. Signal peptides are cleaved inside the RER and the chains are now known as pro-alpha chains.
   4. Hydroxylation of lysine and proline amino acids occurs inside the lumen. This process is dependent on ascorbic acid(Vitamin C) as a cofactor.
   5. Glycosylation of specific hydroxylysine residues occurs.
   6. Triple helical structure is formed inside the endoplasmic reticulum from each two alpha-1 chains and one alpha-2 chain.
   7. Procollagen is shipped to the Golgi apparatus, where it is packaged and secreted by exocytosis.
2. Outside the cell
1. Registration peptides are cleaved and tropocollagen is formed by procollagen peptidase.
2. Multiple tropocollagen molecules form collagen fibrils, via covalent cross-linking (aldol reaction) by lysyl oxidase which links hydroxylysine and lysine residues. Multiple collagen fibrils form into collagen fibers.
3. Collagen may be attached to cell membranes via several types of protein, including fibronectin and integ

Information is provided by Wikipedia

What is Hyaluronic Acid?

Hyaluronic acid is a type of polysaccharide called a glycosaminoglycan. Also known as hyaluronan or hyaluronate, hyaluronic acid occurs naturally in the human body and is central to regulating cell growth and renewal. In fact, it is found extensively in connective, epithelial, and neural cells. As such, hyaluronic acid has found its way into many skin care products, particularly anti-wrinkle formulations. In addition, it has been credited with extending life in those who consume copious amounts in the diet, resulting in the media dubbing hyaluronic acid as the ‘key to the fountain of youth.’

Written by Karyn Maier, Wise Geek

Athletic Business Conference & Expo

Come see what the buzz is all about at the Athletic Business Conference & Expo. Beginning December 2-3, 2010 at the San Diego Convention Center. Over 300 manufacturers, suppliers, architects and consultants from the sports, recreation, fitness, active-aging and medical fitness industries will be exhibiting.

Dr. Smoothie Brands manufacturer of Fresh Face will also be exhibiting while offering samples to taste at their booth#1440. The Athletic Business Conference & Expo features the industry’s leading trade show, a one-stop resource that lets you try and compare the full range of innovative components to build, equip, renovate or operate your facility and programs.

For more information visit http://athleticbusinessconference.com/trade-show/

What is Collagen?

Collagen is a type of protein. Fibrous in nature, it connects and supports other bodily tissues, such as skin, bone, tendons, muscles, and cartilage. It also supports the internal organs and is even present in teeth. There are more than 25 types of collagens that naturally occur in the body.

Collagen is one of the most plentiful proteins present in the bodies of mammals, including humans. In fact, it makes up about 25 percent of the total amount of proteins in the body. Some people refer to collagen as the glue that holds the body together. Without it, the body would, quite literally, fall apart.

Possessing great tensile strength, collagen functions in a manner that is very different from many other types of proteins. For example, it can be found both inside and outside of cells. Collagen fibers are important in contributing to the external structure of cells. However, they are present on the inside of some cells as well.

Collagen works hand-in-hand with elastin in supporting the body’s tissues. Basically, it gives body tissues form and provides firmness and strength; elastin gives the same body tissues much need flexibility. This combination of collagen and elastin is very important in many parts of the body, including, but not limited to, the lungs, bones, and tendons. Even the blood vessels rely on both collagen and elastin.

Often, collagen is discussed in relation to the skin. It works with keratin to provide the skin with strength, flexibility, and resilience. As people age, however, collagen degradation occurs, leading to wrinkles. As such, it is an important substance for those looking for ways to fight the visible effects of aging on the skin. Some skincare professionals actually advise people on ways to stimulate the production of collagen in skin cells.

In addition to being so important in the body, collagen also has many medical uses. It is used in some cosmetic surgery procedures and is sold as a supplement created for joint mobility. It is even used in treating and managing serious burns. For this purpose, it is used in creating man-made skin substitutes.

Since collagens are so important within the body, it stands to reason that collagen deficiencies can be problematic. In fact, there are some genetic diseases that are associated with collagen deficiencies. For example, osteogenesis imperfecta, commonly referred to as brittle bone disease, results from a significantly decreased level of collagen. It can also result from the presence of collagen that is of lower quality than normal.

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Fresh Face will be going to the Club Industry Expo in Chicago IL

In you are in the Chicago area the first part of October, be sure to plan on attending Club Industry Expo beginning October 7-8, 2010. Held at McCormick Place, please stop by booth #839 to learn more about Fresh Face collagen and all of the wonderful benefits of Fresh Face.

The Perfect Gift

If you are looking for the perfect gift to give to a person who has everything, than look no further than Fresh Face.  Fresh Face collagen can be used by women and men alike.

Clinical studies show that as we age, exposed to UV light, non-optimal nutrition & environmental factors, our levels of important amino acids needed to produce collagen can become depleted.

The result? Your skin takes on an aged thinning look, creating folds or fine-line wrinkles. Hair begins to thin out decreasing the overall volume and thickness. Bones become brittle and susceptible to diseases. Joints and connective tissue become worn and painful.

The solution? Fresh Face.

Fresh Face contains 10 grams of Hydrolyzed Collagen, hyaluronic acid and essential nutrients needed for youthful healthy skin, stronger nails and healthier hair. Skin becomes visibly firmer, wrinkles and fine lines begin to fill in for an overall healthy appearance. Fresh Face helps slow the aging process for a youthful radiant look.

Begin to look younger and feel younger by taking Fresh Face daily.

Smoothier Skin, a Healthier You

I love the way a baby skin feels, it is so soft and wonderful. It’s like a breath of fresh air and something you never get tired of.  Wouldn’t it be great if we could drink from the fountain of youth to keep that wonderful soft skin we once had as a baby?

As we begin to age our skin isn’t as soft as it once was, the fine line wrinkles begin to appear not to mention imperfections in the skin and complexion. Though there is no miracle cure, Fresh Face is making a difference in many lives by the way the skin looks and feels. Fresh Face contains hydrolyzed collagen and hyaluronic acid that helps restore skin’s firmness and natural resilience,  rejuvenates skin tone and reduces fine lines and wrinkles.

Beautiful Hair

I sit watching TV and see all of those commercials that focus on healthy hair.  The models on the TV have the most beautiful, shiny hair and makes you wonder how they get it that way.  Do the products they are pushing really work? Will my hair look like that once I’m done? The media really draws us in thinking that if we just buy that certain shampoo product or that coloring product our hair will look just as good.

The reality is no matter how much we try, our hair will never look as good as they make it look on TV. But there is one solution that I am happy to say does work and can help your hair become healthy, it’s Fresh Face. With the collagen you find in Fresh Face it will help your hair grow thicker and healthier. Give Fresh Face a try, you’ll be amazed by the results.

It’s Never to Late to Get Started

Everyday as we begin to get older and we see ourselves aging, this can be heart wrenching. As I sit looking at my own hands comparing them to my own daughters and then to my Mothers it amazing how the process of looking older happens so quickly.

For me, I see myself younger and want to continue to be young. I want to beable to enjoy life and age gracefully. Fresh Face has helped set me on this path.   I can feel better about myself  and look younger by adding Fresh Face to my daily diet. It’s really very simple and takes so little time for the benefits it is providing.

Summer Heat Buster

Start summer off right by drinking a healthy smoothie and look younger while doing it. That’s right, you can add Fresh Face to  a 100% fruit smoothie for the perfect functional collagen beverage.  Not only will you be meeting your daily fruit intake but you’ll be adding more collagen into your diet.

Dr. Smoothie makes 100% Crushed whole fruit smoothie puree that is packed full of delicious fruit and all the benefits fruit has to offer without all of the calories a sugar laden smoothie has.  By adding in Fresh Face first thing in the morning to a Dr. Smoothie will give your body the boost it needs to feel great while firming up the skin, strengthening the nails and hair. A body win win!